is 2010 Mercedes-Benz M-Class ML350 4MATIC a good car?

That model car was decent enough when it was new but now, as a used car, you must chiefly concern yourself with the condition of this specific car. Look up the Carfax history, write down the VIN and call the service dept of a Mercedes Benz dealership ask to see the service history. Some of that service history may be on the Carfax report but best not to rely on any one source of records. Lastly, have the car inspected by your MB tech/business of your choosing. A few hundred dollars in inspection can save you thousands in heartache down the road.

I'm planning to buy one. It looks good now but not sure later on. Would love to hear from the ML350 owners

Pretty good.

http://www.whatcar.com/car-reviews/used/mercedes-b...